Extrapulmonary manifestations of COVID-19

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Nerd alert, there's a lot of nitty gritty details here...   

(depression alert, this isn't pretty either, buckle up cupcakes, this fall is going to be ugly)

And yes, this is why you wear a mask!

https://www.nature.com/articles/s41591-020-0968-3

 

Abstract

Although COVID-19 is most well known for causing substantial respiratory pathology, it can also result in several extrapulmonary manifestations. These conditions include thrombotic complications, myocardial dysfunction and arrhythmia, acute coronary syndromes, acute kidney injury, gastrointestinal symptoms, hepatocellular injury, hyperglycemia and ketosis, neurologic illnesses, ocular symptoms, and dermatologic complications. Given that ACE2, the entry receptor for the causative coronavirus SARS-CoV-2, is expressed in multiple extrapulmonary tissues, direct viral tissue damage is a plausible mechanism of injury. In addition, endothelial damage and thromboinflammation, dysregulation of immune responses, and maladaptation of ACE2-related pathways might all contribute to these extrapulmonary manifestations of COVID-19. Here we review the extrapulmonary organ-specific pathophysiology, presentations and management considerations for patients with COVID-19 to aid clinicians and scientists in recognizing and monitoring the spectrum of manifestations, and in developing research priorities and therapeutic strategies for all organ systems involved.

 

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Bump for facts

my phd buddy was telling me it affects the vascular system...veins...which go everywhere.

The normal flu attacks epithelial tissue, from the outside, causes lots of mucus...  (epithelial tissue includes, skin, GI tract lining, lung lining, etc)

The corona virus attacks from the inside, where the cells that create clotting agents (platelet cells) in the bone marrow, migrate to other organs, causing blood clots, and the resultant complications.  While it's best known for attacking the lungs vascular system with blood clots, it has also been found to cause heart attacks, strokes, kidney damage, extremity damage, etc, due to the thrombocytes.  So technically, it's nothing like the flu whatsoever...