2500 mcg max?

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.....so, I was recently chatting with someone whom would probably know and I am curious if any Zonerz have info on the human body/brain "only" being able to absorb or utilize up to 2500 mcg of LSD. In other words, any dose above that amount has no addituonal effect or benefit. Strange little titbit that has me curious anyway. At any rate, that would clearly be one helluva trip!

sounds like an urban legend to me. i dont have any info that would disprove this, but at the same time, i cant think of any way this could be accurately studied and recorded in a peer reviewed study. the effects of lsd and all psychedelics are so subjective and vary from trip to trip based on set and setting. one day you could eat a few hundred mcg and have a totally manageable trip and the next time you take the same dose it hits you like a ton of bricks. so a person saying "i never feel anything above 2500mcg" is not valid at all...on top of the effects being subjective, you are tripping balls on at least 2500mcg of acid...how the fuck would you know?

there are so many "tour stories" of people doing thumbprints or eating entire sheets that id venture to guess that many people do find value in doses above 2500mcg. for reference, an entire sheet of average strength L would be around 10000mcg, and a thumbprint is significantly more if you take a nice enthusiastic dip into the jar of crystal. ive never done a thumbprint or dosed raw crystal, but i have weighed portions of crystal on an mg scale and i can tell you an enthusiastic thumbprint would be many many times larger than 2500mcg, especially if you lick your thumb first, which i think is the standard practice for the serious thumbprint crowd.

there does seem to be a strange effect with LSD that makes IV injection pretty much the same as eating it. for most drugs, like cocaine or heroin, injecting it drastically changes the effect profile. for instance, if you eat heroin its basically the same as any other strong painkiller, but once you inject a good dose the effects are much more euphoric and extreme, and they come on in a matter of seconds. same for shooting coke. getting a serious bell ringer from a shot of coke is a different world than doing lines...much more akin to smoking crack. but with LSD, IV injection is basically the same as eating it...takes about 30min to come on, and effects are about the same strength...why? this is a question that pharmacology currently has no answer for. it could be related to an upper limit of LSD that can be absorbed in a specific amount of time, or an upper limit of blood plasma levels that can be achieved.

also, claims of blotter or drops of liquid from a vial containing a specific dose are not reliable. you cannot say a square of blotter contains xxxmcg because you have no idea, and because during the laying of the blotter, it often is not 100% evenly laid. in a vial, oftentimes the end of the bottle is stronger than the beginning of the bottle if you get lazy on shaking it up before dosing. get a large amount of L, try small doses first to see where you like to be, and now you have a stash of L at a known dose. when you need to restock, repeat the process. do not give any credence to claims of a specific dose measured in mcg. a scale able to measure in mcg starts at around $1k and a guarantee nobody providing anyone here with L has a mcg accurate scale. if someone hands you doses at a show and says "these are 150mcg", there is absolutley no reason in the world to think they will actually be the same strength as the last doses some guy at a show told you were "150mcg". buy large, test slow and small, dont take L from randos at shows or buy in the lot. period.

even the crystal i weighed out myself does not have an accurate mcg level...i did it with a scale that measures mg and i just had to try the vial to get it to a potency i like...ive got no idea how many mcg are in there and i broke the crystal down myself...so i highly doubt anyone selling broken down material to end users has any actual idea what the doseage is.    

Seems like there should be some definitive answer to this based on all the controlled pre-1966 research on the subject.  

From a purely anecdotal standpoint, don't know if I ever ingested 2,500+ micrograms, but probably came close a few times.   I think seven was the largest number of paper doses, but did take an unknown amount of liquid on a couple of occasions.   However, I personally knew dudes who dosed a lot and they would have to take more and more if they went on a multi-day bender, and before long, they were eating half a sheet at one sitting just to maintain the trip.

2500.....Nice

If it's true that Vitamin C has a "saturation point", then why couldn't other substances also have an upper limit in a similar fashion?

Maybe it's analogous to a computer motherboard that can only utilize a maximum amount of memory?

Or, could it be like increasing sound volume and JND's (just noticeable differences - of each increment)?

idk. 

havent we all had L that was mic'd at say 150, and the same exact crystal mic'd at 300u? 

i think if you took 3500u compared to 2500u, you'd def be higher. no doubt. 

 

Maybe instead of higher, it just lasts longer? 

Mark may be onto something here. Took about 1000 once - no way I coulda got higher but longer def, a poss. I suppose.

At a show in Albany in late 80 s or early 90 s, (they went to Toronto next, 91,maybe,??) A friend of mine had a bottle of liquid w 100 doses in it. I dont know amount other than that etc. According to his wife, who tells the story the best, after selling or giving away about 10-12 doses, the bottle broke in his hand. He cupped his hands to save as much as he could. 

Again, according to her, he had a pretty good puddle in his two hands. They proceeded to call people over to help themselves, and him, by dipping their fingers in, or doing whatever they could to get a dose or 2.

 

So, she has no idea how many doses he "took". All i do know, is as much as this coulda been a story gone bad, it s luckily one of the funniest stories ive ever heard. Unfortunatly, i can not do it justice, you have to hear it from his wife, who for the next 2-3 days had to completly babysit him. They went to the Albany shows, and on to Toronto. Driving back over the border he was still high as hell.

 

So, i dont know how many mcg s were ingested, after hearing this story for years, id say my friend and his wife are convinced that the more you take will def make your journey last longer. He wasnt back to "earth" for almost a full week,  as to thats when he says he felt "normal" again. I cant speak much on whether it will increase your high by increasing dose over a certain amount as his memories of that week are (and have been since day 1) very scattered and blurred. Either that or he chooses not to talk about it much.

But, the stories from his wife are priceless...she usually just says " to give ya the quick version, 4 days later (i think it waz 4), when i drove over the border , "JOHN" was cowering down on passeger seat floor, worried that any border patrol (keep in mind its U.S. - Canadian border 30 years ago) would discover their counterfeit money. (Which they had none of).

To this day, im still looking for ppl who dosed w him and were in that parking lot in Albany.

Thanks Zoner'z! I figured some of y'all may have some valueable input and feedback on this. I had the distinct pleasure of taking liquid twice in '89 along GD tour routes, once from a near empty vile that had indeed chrystalization on the sides of that plastic McCormick bottle which 3 of us cut open and shared around 6 or 7 PM. Wowzerz! That wound up being a lunar 30 hr adventure, somehow complete with a 2 or 3 hour "nap" in the very early morning and followed by a full day of important shit that had to be done - all while still tripping. Crazy Days. Glad that all happened when it did because, "Silly Rabbit, Trips are for Kids!"

i love acid.

me too. tripping often might be for kids, but tripping as a whole is not just for kids. lots of ways you can change your show going habits up to still accomodate psychedelics even as your body ages and your free time shrinks.

doxalymine succinate - otc sleep aid that will knck you the fuck out and is not fevery or weird at all like benadryl. if you need to get some sleep, pop some of this and the last quarter of your acid trip stands no chance

modafinil/armodafinil - wakefulness promoting agent that gives all the benefits of amphetamine but without the high. makes you feel like you got a full 8 hours of deep restful sleep and are ready to take on the day within 45min after dosing. mostly nonaddictive and easy on the body

kratom/tylenol combo - best thing ive found to combat muscle tension related pain

and get a seat! even when im not tripping its hard for me to stand for a whole show without pain. you zoners that are decades older than me and ride the rail every night blow my mind...looking at you lltd!

Taking more than 150 mics is a waste of good LSD.

^ Completely subjective thing to make such a declarative statement regarding.

I'll take under ~150 mics if I'm playing music with folks and need to keep grounded to an extent where I can communicate and express my ideas fluidly without issue.  

I saw Tool in November and took 4 fatties which I suspect at 350-400 mics total and had a "religious experience".

No LSD was "wasted".

Daylight- thanks for the info.  I always appreciate your input on these subjects.

Naked Veneta poll humping guy is all well and good when you are watching him on video from the comfort of your home. Not so much when he is dancing next to you during a show. Recently found a really sweet party area near the south entrance of Yosemite. Closed golf course with a club house and pool, RV campground, and an owner willing to rent it out to 300 people for a weekend party. That got shut down because some idiot got naked and broke into one the senior citizens Reagan Republicans house up the road while they were home. 

I've had to babysit way to many people who ventured beyond 150. Don't do it in public unless you know what the fuck you are doing. 

lol @ thom.....i suspect lots of L was wasted on you over the decades. 

the more gorgeous the L, the more i want to eat at one time. 

thom - i still stand by my statement that estimates of the "mics" you are taking are tenuous at best for 95% of people, but typically for me, what i assume would be around 150 mics is vastly different from what i assume would be around 300 mics, in both quality of the experience, and the impact it has on your perception of live grateful dead music. i prefer to talk in terms of average strength blotter from within the last 5-10 years, and for me 3-4 is typically an average dose, and id guess each average square would be around 75mcg, although more people claim them as 100-150mcg, i think in many cases the strength gets exaggerated down the line.

higher doses provide more consistent peak experiences. i do not recommend this to anybody, and i do not give these doses to anybody except one very close friend, but ime 5-7 squares of average strength blotter(what i would assume is around 375-525mcg) provide a consistent peak experience that i can still mostly tolerate in public if i have a seat.

honestly, under 4 or so average strength blotters that i would assume is around 300-400mcg is almost not even worth it. i find that if within the first few hours im not holding on for dear life a bit, the experience as a whole is a bit underwhelming. again, not something id recommend to anyone. i discovered my preferences and tolerances by being young and stupid. 

siobud, i had a similar experience with tool. 7 drops, bart ride home was a surreal nightmare but it was one of my best heavyhanded concert experiences of all time.

StrawBud, my wife and I saw the 10/31/95 Phish show in Rosemont, IL.

Had an "empty" vial, so I cut it half and dropped it in a shared bottle of water.

We were barely hanging on even before we hit the turnstiles.

Parted ways to use the restroom and somehow both made it to our seats.

She had to throw up while in the bathroom.

Good thing we had 2nd row center or things may have turned out much differently.

Nothing else to do but laser focus on the show!crying

Flying solo works well.