In brief, they were surprised that two distinctly different types of mushrooms evolved different biochem processes to make the same compound. But they don't know why.
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"The research not only paves the way for improved production methods but also raises profound questions about the ecological role of psilocybin. Deciphering why evolution repeated itself to create two unique biochemical paths to the same molecule may uncover fundamental principles governing fungal survival strategies, chemical communication, and niche adaptation. Such knowledge could revolutionize how scientists harness fungi to produce bioactive molecules and comprehend microbial ecosystems’ chemical language.
In conclusion, this remarkable discovery expands the frontiers of natural product chemistry and fungal biology by revealing that psilocybin production is not the province of a single enzymatic lineage but arose independently in separate fungal clades. This dual evolutionary origin of psilocybin exemplifies nature’s biochemical ingenuity and provides fertile ground for biotechnological innovation, therapeutic development, and ecological research. The study encapsulates a vital step toward decoding the mysteries of psychedelic mushrooms and harnessing their molecular treasures responsibly.
https://bioengineer.org/scientists-discover-and-synthesize-active-compou...
Top of Page Bottom of Page PermalinkFull Name: BraMance jlp
on Thursday, September 25, 2025 – 02:55 pm
super interesting
super interesting
thanks for sharing
Top of Page Bottom of Page PermalinkFull Name: Alan R StoneSculptor
on Thursday, September 25, 2025 – 03:39 pm
"Research suggests that mushrooms likely produce psychedelic compounds like psilocybin as an evolutionary defense mechanism to deter insects and other predators.
The compound interferes with animal nervous systems and mimics the neurotransmitter serotonin, causing disorienting effects that can discourage the animals from eating the fungi....
Other possibilities have been proposed, though they have less supporting evidence.
Digestive aid for spores: Some speculate that psilocybin might act as a laxative or cause vomiting in animals, helping to spread the spores more effectively.
Manipulation of larger animals: Another idea is that mushrooms actively manipulated larger animals, such as humans, through their psychoactive compounds to promote a symbiotic relationship. However, this is largely speculative and not widely accepted by the scientific community. "
Top of Page Bottom of Page PermalinkFull Name: dimethyllovebeam joe
on Thursday, September 25, 2025 – 05:54 pm
14g is an inspiring dose.
14g is an inspiring dose.
Top of Page Bottom of Page PermalinkFull Name: Philzone Refugee Herbal Dave
on Friday, September 26, 2025 – 11:21 am
The bears aren't dancing,
The bears aren't dancing, they're just trippin' balls?