Some Cold Morning Stuff: Kesey, comedy, and new LSD research

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If you have some time to kill today, here's some random stuff to keep you occupied:

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Ken Kesey describes his first LSD trip

https://www.youtube.com/watch?time_continue=408&v=ujxXdGZ8PLo

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Marc Maron: Jerry Garcia Mushroom Trip (comedy)

https://www.youtube.com/watch?v=yAxUsb1P4aI

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Effective connectivity changes in LSD-induced altered states of consciousness in humans (jan 28, 2019)

https://www.pnas.org/content/early/2019/01/23/1815129116

https://www.inverse.com/article/52797-lsd-trip-psychedelic-serotonin-rec...

An LSD study published Monday in PNAS provides further evidence for a leading theory, suggesting that the brain on LSD trips because it’s experiencing sensory overload....LSD has well-known effects on serotonin, a neurotransmitter involved in many other psychedelic drugs, and it’s been proposed that serotonin is also the key molecule involved in messing with the thalamus’s ability to filter information during an LSD trip, resulting in “an overload of the cortex.” So, Preller and her team tested what would happen if they gave people LSD but blocked their serotonin receptors.

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look familiar? 

"An LSD study published Monday in PNAS provides further evidence for a leading theory, suggesting that the brain on LSD trips because it’s experiencing sensory overload."

Well duh.  The brain acts as a regulating device, organizing your sensory input so that you can function in the "real" world. That's how it has evolved over millenia, it's what allows our consciousness to experience the material world.  LSD interrupts that organizing function, allowing more input than the brain is used to dealing with.  The governor is disabled.  The more you take, the more it is disabled.  Which is why people who take too much can flip out; so much sensory overload that the brain can no longer make any sense of it. And the brain has evolved to make sense of it, that's it's function. 

A good dose allows you to experience the greater reality (what many would call having a transcendental experience) without completely (literally) losing your mind. 

Thanks for posting, it's good to see that the world is starting to pay attention to this.

Bear Stanley: Reflections on Life, LSD and DMT

https://www.youtube.com/watch?v=geRXSVuPRhU&feature=youtu.be

"Lawyers and doctors, you've got to be careful."